Stat6 molecular weight

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August undefined, 2024

WebSTAT6 is tyrosine phosphorylated (Tyr641) in response to cellular interaction with IL-4. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 and Th9 immune response (2). WebDec 10, 2024 · Author summary STAT6 is a transcriptional factor that plays an important role in the extracellular cytokine and virus-mediated immune response. Extensive studies have revealed that the dysregulation of STAT6 is linked to the pathological features of virus-associated cancers. However, the molecular mechanism of STAT6 regulation by tumor …

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WebHuman STAT6 has three isoforms; the molecular weights are 94, 82 and 74kD. The immunogen (phosphorylated peptide) is shared by these three isoforms. This antibody recognizes STAT6 Phospho (Tyr641) in all three isoforms. The predominant band detected is at 94 kD. Clone A15137E does not react with mouse. WebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. STAT6 INFORMATION. Proteini. Full gene name according to HGNC. Signal transducer and … matrix chinese name

Recombinant Human STAT6 GST (N-Term) Protein - Novus Biologi…

WebThe MA5-15659 immunogen is purified recombinant fragment of human STAT6 expressed in E. Coli. MA5-15659 detects STAT6 which has a predicted molecular weight of approximately 94kDa. Target Information STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. WebSTAT6 (predicted molecular weight 94kDa) has been found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL-4. WebOct 14, 2011 · We now show that STAT6 is required for innate immune signaling in response to virus infection. Viruses or cytoplasmic nucleic acids trigger STING (also named MITA/ERIS) to recruit STAT6 to the endoplasmic reticulum, leading to STAT6 phosphorylation on Ser (407) by TBK1 and Tyr (641), independent of JAKs. … matrix churchill case

STAT6 Antibody (NBP1-85345): Novus Biologicals

PE Mouse Anti- Stat6 (pY641) - BD Biosciences

WebSignal Transducer and Activator of Transcription 6 (STAT6) is a member of the Janus family tyrosine kinases (Jak)/ STAT signal transduction pathway and mediates cytokine … WebDespite its predicted molecular weight, IL-33 will often run at higher molecular weight in SDS-PAGE. Studies have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine, and an intracellular nuclear factor with ... matrix chernoff inequalityWebMay 1, 2024 · Part of the Methods in Molecular Biology book series (MIMB,volume 1966) Abstract Activation of signal transducer and activator of transcription 6 (STAT6) is a key signaling pathway in macrophage function, and is required for the so-called alternative (M2) activation of macrophages. matrix churchill

"WebStat6 is then released from the receptor, dimerizes, and is thought to contact the basal transcription machinery by binding to p300/CBP. While Stat6 is widely expressed in … " - Stat6 molecular weight

Stat6 molecular weight

Stat6 Antibody Cell Signaling Technology

WebSTAT6 fusion protein Ag0410: Full Name: signal transducer and activator of transcription 6, interleukin-4 induced: Calculated molecular weight: 100 kDa: Observed molecular weight: 95 kDa: GenBank accession number: BC005823: Gene symbol: STAT6: Gene ID (NCBI) 6778: Conjugate: Unconjugated: Form: Liquid: Purification Method: Protein A ... WebAug 26, 2024 · As a matter of fact, the final model simulation by Takahashi et al. (2024) suggested the following doses according to metabolizer status and weight to achieve target trough concentrations of 1.5–5.0 mg/L: for normal metabolizers: 16 mg/kg (15 kg weight), 12 mg/kg (15–30 kg weight), or 10 mg/kg (30 kg weight); doses were 33–50% lower for ...

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WebAnti-STAT6 antibody (ab88540) Datasheet Submit a review Submit a question References (1) Key features and details Mouse polyclonal to STAT6 Suitable for: WB, ICC/IF Reacts with: Human Isotype: IgG Get … WebMay 8, 2024 · Macromolecule Content Total Structure Weight: 18.26 kDa Atom Count: 884 Modelled Residue Count: 118 Deposited Residue Count: 164 Unique protein chains: 2 Display Files Download Files 5NWX Insight …

WebApr 6, 2024 · To validate the potential mechanisms of QCWZD on UC and UCAC, dextran sodium sulfate (DSS, molecular weight: 36,000–50,000 Da, MP Biomedicals) and carcinogen azoxymethane (AOM, Sigma-Aldrich)-induced C57BL/6 mice were adopted to validate the protective effect of QCWZD on colitis and CAC. WebSTAT6 (predicted molecular weight 94kDa) has been found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL-4. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the ...

WebStat6 Antibody detects endogenous levels of total Stat6 protein. Species Reactivity: Human, Mouse, Rat Species predicted to react based on 100% sequence homology: The antigen sequence used to produce this antibody shares 100% sequence homology with the … WebOct 24, 2011 · STAT6 is expressed in normal kidneys (Fig. 1 A and B) yet the absence of PY-STAT6 indicates that it is normally kept in an inactive state. To test whether STAT6 can …

WebMA5-15659 detects STAT6 which has a predicted molecular weight of approximately 94kDa. Target Information STAT6 protein is a transcription factor activated by cytokines, …

WebImmunogen: Phosphorylated Human Stat6 (pY641) Application: Intracellular staining (flow cytometry) (Routinely Tested) Target Molecular Weight: 100 kDa Vol. Per Test: 20 µl RRID: … matrix cinema headphones youtubeWebOct 24, 2011 · Treatment of bpk mice from postnatal days 7 to 21 with 1.4 mg/kg teriflunomide every 2 d, a clinically relevant dose, results in a very similar—or even stronger—suppression of renal cyst growth compared with genetic inactivation of the STAT6 gene (Fig. 4B). Kidney weight (Fig. 4C) and cystic index (Fig. 4D) are significantly reduced … herbert\u0027s wine jelly llcWebα-MMC regulates cytokine release from monocytes matrix cinema headphones manualWebJan 13, 2013 · SFT-10 and SFT-44 tumors both express the smaller, more common 90-kDa NAB2-STAT6 fusion. MW, molecular weight; WT, wild type. Arrowheads indicate NAB2-STAT6 fusion proteins. (c) ... matrix cinema wireless rtingsWebJan 13, 2013 · SFT-14 tumor expresses the larger 150-kDa NAB2-STAT6 fusion protein. SFT-10 and SFT-44 tumors both express the smaller, more common 90-kDa NAB2-STAT6 … matrix chiffreWebMyBioSource.com's STAT6 (Ab-645) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. ... Antigen STAT6; Molecular Weight 81,748 Da; Host Rabbit; Immunogen The antibody detects endogenous level of total STAT6 protein; matrix choose pillWebSTAT6 (phospho Y641) was immunoprecipitated from 0.35 mg Daudi (Human Burkitt's lymphoma lymphoblast) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate 10ug with … herbert\u0027s tea rooms tissington